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Using Atomic Force Microscopy for biomaterial and regenerative medicine research  

Yale University Tuesday Technology Talk
October 22, 2019 

Discover where Modern Atomic Force Microscopy (AFM) can take your Research

Atomic Force Microscopy has long been used to explore the world at the nanometer scale. Yet due to the limitations of early AFMs, the technique was not fully applicable or adopted widely for use in practical work in the fields of biomaterials and regenerative medicine. For example, early AFMs were not easily able to work in or around fluid, required significant sample constraints, and were painfully slow to use.

Even in areas where AFM offered a distinct advantage for measuring biomaterials, like using force curves to measure mechanical properties of soft materials, the lack of easy calibration of all instrument parameters left users with semi-quantitative and difficult to interpret data in all but the best of cases. With recent developments and improvements to design, hardware, software, and new modes, AFM has overcome these historic challenges and is now a transformational technique available to characterize previously difficult materials and work under a wider range of measurement conditions.

This talk will provide a brief history of AFM, explore the needs of the bio/regenerative medicine field, and highlight where AFM can be applicable to solve problems in this research space. There will be plenty of pertinent examples of work already done and a look into future work possible with a modern AFM.

Who Should Attend?

Anyone who is looking to learn about advances in measurement technology and is curious if this technique is applicable for them. Although many of the examples are targeted towards measurements in biomaterials, this topic can be seen as a proxy for any difficult to handle sample or measurement condition set. There will be plenty of time for discussions and ‘Ask the Expert’ sessions for those interested in learning more about their particular samples and applications.


Yale University
West Campus Analytical Core
800 West Campus Drive, Room 218
West Haven, CT 06516
Lunch will be served

Campus Map


Drew Griffin, Asylum Research