AFM's ability to directly interact with samples at the nanoscale and in near-physiological conditions enable novel insights into the structure and nanomechanical properties of living samples. AFM is especially useful in understanding the mechanical properties of the extracellular environment. However, quantitative measurements of these properties are often stymied by a number of experimental and instrumentational parameters. Dr. Nicholas A. Geisse presents an overview of AFM for mechanobiology.
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Dr. Nicholas A. Geisse, Chief Science Officer of NanoSurface Biomedical, Seattle